
Cats do not produce the enzyme responsible for initiating carbohydrate digestion called amylase in their salivary glands. 4, 5 In addition, cats also have low activities of intestinal and pancreatic amylase and reduced activities of the intestinal enzymes called disaccharidases, that break down carbohydrates in the small intestines. 4, 5 In their natural habitat, cats consume prey high in protein with moderate amounts of fat and minimal amounts of carbohydrate; thus, they are metabolically adapted for higher metabolism of proteins and lower utilization of carbohydrates than dogs or other omnivores. 1 Most commercial diets for cats are formulated with a mixture of animal- and plant-derived nutrients, most commonly in dry kibble form that requires carbohydrates for the expansion and cooking process.
Full Answer
What enzymes are in a cat's digestive system?
There are three main enzymes in the digestive system of a cat; amylase, protease, and lipase. Amylases are responsible for breaking down carbohydrate foods into simple sugar molecules. Protease enzymes break down protein into amino acids and lipases break down fats into fatty acids and triglycerides.
What does a high amylase level mean in a cat?
"The amylase level, which is a pancreas enzyme, is elevated. Unfortunately, this enzyme is not reliable in cats, so this elevation has no significance." the six year-old's CPK is 1073 out of 56-529 and doesn't that imply muscle wasting?
Do cats need enzymes?
When cats don’t produce enough of their own natural enzymes, we supplement these in their diet. Commercially available enzymes often come in powder or capsule form and include the three main enzymes amylase, lipase and protease.
Should I be worried if my cat has elevated liver enzymes?
Don’t panic! We’ll walk you through liver diseases in cats, reasons, and causes for elevated levels of enzymes. We’ll come to know when to worry about our furbabies, symptoms and telltale signs of elevated liver enzymes, and treatment options.

What food should I feed my cat with pancreatitis?
Either dry or wet food or a combination of both is typically fine for most felines, although older cats may do better with wet food. In addition, you can supplement their diet with cat safe fruits and veggies, bits of tuna, or pieces of skinless, cooked chicken or turkey.
How much should I feed my cat with pancreatitis?
Cats with chronic pancreatitis should eat about six small meals a day.
Do cats with pancreatitis need a special diet?
A low-residue diet might be the diet of choice in a cat that only has pancreatitis, but if concurrent intestinal disease is present, then a novel protein diet might be a better choice. The caveat for owners is that the cat must eat.
Is bone broth good for cats with pancreatitis?
Bone Broth: This can be soothing for a cat's GI tract; it can provide collagen, glucosamine, and minerals and may also help coax a cat with no appetite to eat again.
What does high amylase in cats mean?
Amylase (AMYL): Elevations in this test indicate pancreatitis or kidney disease. Aspartate aminotransferase (AST): Increases in this test may indicate liver, heart or skeletal muscle damage.
Is salmon OK for cats with pancreatitis?
Digestion isn't as efficient in pancreatic cats so you'll see muscle loss, which is due to insufficient protein absorption, made worse by poor quality proteins. There is a long list of foods to avoid or reduce. Examples are salmon, sardines, cheese, yogurt, tofu, peanut butter, bacon, and other high fat products.
How can I treat my cats pancreatitis at home?
Feline pancreatitis cannot be treated at home. In the veterinary hospital, a cat with pancreatitis will receive intravenous fluid. By taking a short break from eating and drinking, it gives the cat's pancreas time off from sending out digestive enzymes.
Do probiotics help cats with pancreatitis?
Yes, probiotics for cats with pancreatitis are an effective form of treatment. Probiotics may provide relief from signs and symptoms like pain and inflammation.
How do you fix pancreatitis in cats?
One of the most common anti-nausea medications, maropitant (Cerenia), has also been shown to help decrease abdominal pain in animals. If additional pain medication is needed, opioid medications such as buprenorphine may be prescribed. Early nutritional support is key in the treatment of feline pancreatitis.
Is tuna OK for cats with pancreatitis?
Tuna is high in unsaturated fat, like omega fatty acids. These are a good type of fat, but if your cat is consuming an inappropriate amount of fat regularly, they could be susceptible to conditions like pancreatitis or steatitis, which is inflammation of the pancreas or fat tissues, respectively.
Is pumpkin good for cats with pancreatitis?
Canned pumpkin with no spices or pulped raw pumpkin is best. Digestive enzymes are a must for all pets dealing with pancreatic disease. If they are to have a proper chance of recovery, this is a must. This takes the pressure off of the pancreas to produce all of the enzymes needed for digestion.
Do cats with pancreatitis drink a lot of water?
A pet with pancreatitis will exhibit some or all of the following signs: lack of appetite, frequent vomiting and diarrhea which may contain blood. A pet may also drink more water than usual and vomit it soon after consumption.
Do cats with pancreatitis drink a lot of water?
A pet with pancreatitis will exhibit some or all of the following signs: lack of appetite, frequent vomiting and diarrhea which may contain blood. A pet may also drink more water than usual and vomit it soon after consumption.
How can I treat my cats pancreatitis at home?
Feline pancreatitis cannot be treated at home. In the veterinary hospital, a cat with pancreatitis will receive intravenous fluid. By taking a short break from eating and drinking, it gives the cat's pancreas time off from sending out digestive enzymes.
How can I get my cat to eat after pancreatitis?
With pancreatitis, it is a matter of giving “supportive care” until the pancreas heals on its own. And unfortunately, some cats remain so nauseated that they will not eat, requiring a temporary feeding tube. This allows the cat to be home and receive nutrition and medications until he starts eating on his own.
Can Overeating cause pancreatitis in cats?
Overweight, obese cats, or cats with a high-fat diet are at high-risk for developing pancreatitis (and other problems), so pay attention. Cat's rarely come to us to tell us they are uncomfortable or ill. Their instincts make them very stoic, so these symptoms are often overlooked.
Are digestive enzymes safe for cats?
In general, digestive enzymes that are of good quality and from a reputable source, are safe for cats. There have been some reported side effects t...
What digestive enzymes are good for cats?
Cats need three digestive enzymes to process their food; amylase, lipase and protease
What are the symptoms of lack of digestive enzymes?
Symptoms can include but aren't limited to; vomiting, diarrhea, poor coat quality, altered appetite (sometimes increased), bloating, weight loss, l...
What are the side effects of digestive enzymes?
Side effects can include; vomiting, diarrhea, oral ulceration. Side effects are usually rare.
What is the connection between cat nutrition and health?
While there are numerous papers discussing the connection between feline nutrition and health, few are as good as "The carnivore connection to nutrition in cats" by Dr. Debra L. Zoran of the College of Veterinary Medicine at Texas A&M University. In this article Dr. Zoran notes that "although cats have adjusted to most manufactured diets, the limitations of substituting animal-origin nutrients with plant-origin nutrients in foods formulated for cats are being increasingly realized.” 1 In this same article Dr. Zoran points out how diets with inappropriate amounts of carbohydrates and plant based protein are likely responsible for obesity, hepatic lipidosis (fatty liver syndrome), inflammatory bowel disease and diabetes in cats.
What hormones increase circulating glucose levels in cats?
Other counter-regulatory hormones that similarly contribute to increasing circulating glucose levels include glucagon, epinephrine, cortisol and growth hormone. As a result of the counter-regulatory effect of thyroid hormones, cats with hyperthyroidism frequently develop glucose intolerance and insulin resistance.
What happens when you have high insulin levels?
The chronically elevated levels of insulin that occur with hyperinsulinemia lead to persistent lipogenesis and the ongoing production of fat. Simply put, carbohydrate intake leads to insulin release which leads to fat accumulation.
How does insulin work?
Insulin's job is to control the level of glucose in the blood stream. Insulin's role in health is critical as excessive glucose levels, as occur with untreated diabetes mellitus, are toxic. Insulin release is triggered by increases in the glucose level in the blood. In response to increasing levels of insulin in the blood, glucose is removed from the blood stream and stored in the form of either glycogen in muscle and liver tissue, or fatty acids in adipose (fat) tissue. Elevated levels of insulin in the blood stream called hyperinsulinemia occur following the consumption of many forms of carbohydrate. Persistently elevated levels of insulin in the blood stream ultimately lead to down-regulation of the insulin receptors causing insulin resistance that if untreated often progresses to type II diabetes. Because of insulin's potent induction of fat storage, hyperinsulinemia is also a potent cause of obesity.
Why do carbohydrates cause obesity?
Diets high in carbohydrates stimulate regular spikes in circulating insulin levels that lead to the storage of circulating fatty acids in adipose (fat) tissue. This process is a major factor in the weight gain that leads to obesity.
How does insulin release occur?
Insulin release is triggered by increases in the glucose level in the blood. In response to increasing levels of insulin in the blood, glucose is removed from the blood stream and stored in the form of either glycogen in muscle and liver tissue, or fatty acids in adipose (fat) tissue.
Why does my cat have diarrhea?
Dietary intolerance is an important non-immune cause of gastrointestinal tract symptoms (eg, vomiting and diarrhea) in cats. It can be caused by a variety of additives in cat foods including artificial colors, flavors and preservatives as well as the actual protein and carbohydrate sources utilized in the diet.
What causes a cat to have a swollen stomach and vomiting?
EPI might be the result of pancreatitis , or a chronic inflammation of your cat's pancreas. Cats with this disease often also suffer from diabetes mellitus, so you're dealing with daily insulin injections as well as digestive enzyme supplementation. Symptoms of pancreatitis include appetite loss, vomiting and abdominal pain. Among the tests run to diagnose pancreatitis is the panreatic lipase immunoreactivity, measuring the amount of lipase in Kitty's blood. Your vet might give your cat intravenous fluids to replace those lost from vomiting, along with pain medication. As your cat recovers, your vet might recommend digestive enzyme supplementation.
What enzymes do cats need to digest food?
Your cat's pancreas produces digestive enzymes to help him digest proteins, starches and fats. Commercial digestive enzymes, in powder form, are meant to be mixed with your cat's food as a supplement. Don't use digestive enzymes marketed for people or other species for your cat. Typical enzymes available in a commercial preparation include amylase, which converts starch into monosaccharides or simple sugars; protease, which aids in protein digestion; and lipase, which breaks down fats. While generally safe, digestive enzymes shouldn't be given to cats with liver or kidney disease or those that are pregnant or nursing.
Why does my cat's poop stink?
If the pancreas doesn't produce enough enzymes, your cat can suffer from exocrine pancreatic insufficiency. Symptoms of EPI include weight loss even though your cat is always hungry, along with chronic diarrhea. Not only will your cat's stools be loose and profuse, but they'll really stink, too. You might also notice a high incidence of feline flatulence. Some cats develop an oily hair coat. The condition generally strikes cats of middle age or older.
Who is Jane Meggitt?
Jane Meggitt has been a writer for more than 20 years. In addition to reporting for a major newspaper chain, she has been published in "Horse News," "Suburban Classic," "Hoof Beats," "Equine Journal" and other publications. She has a Bachelor of Arts in English from New York University and an Associate of Arts from the American Academy of Dramatics Arts, New York City.
What happens if a cat's pancreas is inflamed?
If the pancreas is inflamed, the digestive enzymes become active before leaving the pancreas, breaking down fat and proteins in the pancreas and other organs; essentially, Missy's body is digesting itself. If the enzyme activation is significant enough, a cat can develop acute pancreatitis, ranging from mild to life threatening.
What is the pancreas of a cat?
In a healthy cat, digestive enzymes pass through the pancreas in an inactive state to the small intestine, where they activate to aid digestion.
What to do if Missy has pancreatitis?
Her pancreas will need a rest to stop the flow of the enzymes causing the problems, so she'll require intravenous fluids to keep her fluid and electrolyte levels stable. It's very difficult to pinpoint a cause for pancreatitis, though sometimes a parasite or infection, such as feline distemper, can trigger the condition. In the very rare occasion the cause of the illness is determined, the vet will also address the trigger. The prognosis depends on the severity of the pancreatitis, as well as how the cat responds to treatment. In most cases, mild forms of acute pancreatitis have a good outlook with aggressive treatment.
What does it mean when your dog has high amylase?
High amylase levels can indicate kidney disease, gastrointestinal issue or the effects of certain medications. Lipase, the other enzyme produced by the pancreas, is often also elevated in these conditions. If Missy's amylase and lipase levels are high, the vet will look at other values in her blood work, as well as her medical history and symptoms.
What does Missy's pancreas produce?
Jupiterimages/Comstock/Getty Images. Missy's pancreas produces hormones to regulate her body functions and enzymes to aid in food digestion. Blood work may reveal high levels of enzymes in the pancreas. However, the enzymes measured in routine blood tests aren't limited to her pancreas, and vets don't often rely on their values to diagnose ...
What is the prognosis for a cat with pancreatitis?
The prognosis depends on the severity of the pancreatitis, as well as how the cat responds to treatment. In most cases, mild forms of acute pancreatitis have a good outlook with aggressive treatment.
Which organ secretes two enzymes?
The pancreas secretes two enzymes, serum amylase and lipase, which theoretically would indicate the organ's health. However, other organs produce or excrete the enzymes, so high levels can indicate other ailments.
Cat Liver Enzymes Over 500: First Steps
We can confirm cat liver enzymes over 500 can come through a biochemical profile. The elevation doesn’t always imply liver disease. Since it can denote an underlying condition for other organs, not necessarily connected to the liver.
What Causes Elevated Levels of Liver Enzymes in Cats?
Elevated liver enzymes in cats could suggest various conditions and illnesses. The liver might not always be the source behind the high count of enzymes, as other organs might be producing the same enzyme.
What Do Liver Enzymes Do?
Enzymes are catalysts that boost the rate of chemical reactions within the cells. Liver diseases, and elevated counts of liver enzymes, happen for various reasons. They occur due to damage in the liver cells.
Can Cats Get Liver Diseases?
Liver diseases in cats are extremely common. They can affect cats regardless of their age and breed. So, kittens and older cats are both prone to liver diseases. The healthiness of the liver plays a vital role in the overall healthiness of the cat.
Symptoms of High Liver Enzymes in Cats
Cats with liver disease showcase a variety of symptoms. If you notice some of these symptoms on your furbaby, book an appointment with a vet immediately. Liver disease can be life-threatening. So early diagnosis and treatment are crucial for an increased probability of recovery.
Is There a Treatment for Elevated Levels of Liver Enzymes?
High levels of liver enzymes are luckily treatable. The liver’s regenerative nature increases the chances of recovery, which is why liver failure is uncommon.
To Sum Up
Cat liver enzymes over 500 could indicate the presence of liver disease or other underlying issues that can cause that elevation. Early discovery and accurate diagnosis are crucial for a healthy and successful recovery. If you happen to notice any changes with your pet, head to a vet for an accurate diagnosis.
What organs do cats have?
The liver is the largest internal organ in the cat (and in humans, too!) and has many important functions. You can read all about what the liver does in cats and the related potential health problems in our article Liver Disease In Cats. These health issues include things like liver cancer, inflammation of the gallbladder and even poisoning.
Why is AST more sensitive in cats?
AST can be more sensitive in cats for some types of liver disease such as the granulomatous inflammation found in FIP, but is also produced by muscle damage. Bilirubin is also included in the test. This is not an enzyme, but a product of hemoglobin breakdown that becomes part of the bile.
How to look at a cat's liver?
Touching the cat’s abdomen to feel the liver and its size. Looking at the cat’s gums, the membranes under the eye and other tissues to look for jaundice. Using an ultrasound to look for changes in the liver’s inner structure. Taking a biopsy and look at the liver cells under a microscope.
What is an enzyme?
First, a recap on what an enzyme is. In a nutshell, enzymes are proteins that can break apart specific large molecules into smaller ones. They can also create specific new compounds by putting together smaller molecules. Essentially, they are one of the body’s tools to manage its biochemistry.
Is the liver good for cats?
The liver is an amazing organ with a lot of different functions, and it is remarkably good at repairing itself when damaged. While cats that have liver disease can look like they are dying (or want to die), given enough supportive care and specific treatment, most survive and become healthy again. </blockquote >.
Can cats have elevated enzymes?
Dr. Miller says that benign elevation of enzymes is rare in cats.The exception would be with elevated levels of ALP (Alkaline Phosphatase) in kittens. This can happen due to rapid bone growth, as osteoblasts – cells involved with bone formation – also produce ALP. In kittens, this can be a benign finding.
What is the pancreas?
What is pancreatitis? Pancreatitis is a disease caused by inflammation of the pancreas. The pancreas is a small fleshy organ located between the stomach and small intestine. The pancreas has many functions related to digestion and the regulation of blood sugar levels.
What is the test for pancreatic lipase?
Pancreas-specific lipase is measured with a test called Feline Pancreatic Lipase Immunoreactivity , known simply as fPLI. The test requires only a simple blood test. A fasting sample is preferred, but it is not essential for the accuracy of the test.
What is the condition of a cat that has been diagnosed as diabetic?
Cats with liver and/or intestinal disease (which often accompanies pancreatitis in the cat). Cats that have been recently diagnosed as diabetic or diabetic cats with poorly controlled disease (these cats may have underlying pancreatitis which makes the diabetes harder to control).
Which enzymes are not useful for diagnosing pancreatitis in dogs?
Two enzymes that have a small role in diagnosing pancreatitis in the dog, called serum amylase and serum lipase, are not useful in diagnosing pancreatitis in the cat.
What are the symptoms of a cat with a pancreatitis?
Clinical signs are often vague and non-specific, and include lethargy, poor appetite, weight loss, and dehydration.
What blood test can show pancreatitis?
Routine blood tests such as the Complete Blood Count and Biochemistry Profile (see handouts: "Complete Blood Count" and "Serum Biochemistry") usually reveal a variety of changes, but these are not specific for pancreatitis; most indicate involvement of other organ systems.
Is a FPLI test good for cats?
Studies have demonstrated that the fPLI test is highly reliable for diagnosing pancreatitis in cats with moderate to severe pancreatitis. Cats with mild disease are more difficult to diagnose reliably. However, fPLI out-performs all other blood tests and is currently considered the best blood test available for diagnosing pancreatitis in cats.
